Zaini is a surname. Notable people with the surname include:
Helmy Faishal Zaini (born 1972), Indonesian politician
Hill Zaini (born 1987), Bruneian singer and actor
Jassim Zaini (1943–2012), Qatari artist
Mohd Annuar Zaini (born 1951), Malaysian administrative figure
Shahrin Zaini (born 1985), Bruneian former footballer
Shahrol Yuzy Ahmad Zaini (born 1976) Malaysian motorcycle Grand Prix rider
Yahya Zaini (born 1964), Indonesian politician
